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SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity

BACKGROUND: Multiple sclerosis (MS) is a chronic, debilitating condition characterized by CNS autoimmunity stemming from a complex etiology involving both environmental and genetic factors. Our current understanding of MS points to dysregulation of the immune system as the pathogenic culprit, howeve...

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Detalles Bibliográficos
Autores principales: O’Connell, Patrick, Blake, Maja K., Godbehere, Sarah, Amalfitano, Andrea, Aldhamen, Yasser A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533612/
https://www.ncbi.nlm.nih.gov/pubmed/36199066
http://dx.doi.org/10.1186/s12974-022-02594-9