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A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave

Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty. At this early stage of an epidemic, where no vaccine or medical treatmen...

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Autores principales: da Costa Avelar, Pedro Henrique, del Coco, Natalia, Lamb, Luis C., Tsoka, Sophia, Cardoso-Silva, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533637/
https://www.ncbi.nlm.nih.gov/pubmed/37520620
http://dx.doi.org/10.1016/j.health.2022.100115
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author da Costa Avelar, Pedro Henrique
del Coco, Natalia
Lamb, Luis C.
Tsoka, Sophia
Cardoso-Silva, Jonathan
author_facet da Costa Avelar, Pedro Henrique
del Coco, Natalia
Lamb, Luis C.
Tsoka, Sophia
Cardoso-Silva, Jonathan
author_sort da Costa Avelar, Pedro Henrique
collection PubMed
description Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty. At this early stage of an epidemic, where no vaccine or medical treatment is in sight, algorithmic prediction can become a powerful tool to inform local policymaking. However, when we replicated one prominent epidemiological model to inform health authorities in a region in the south of Brazil, we found that this model relied too heavily on manually predetermined covariates and was too reactive to changes in data trends. Our four proposed models access data of both daily reported deaths and infections as well as take into account missing data (e.g., the under-reporting of cases) more explicitly, with two of the proposed versions also attempting to model the delay in test reporting. We simulated weekly forecasting of deaths from the period from 31/05/2020 until 31/01/2021, with first week data being used as a cold-start to the algorithm, after which we use a lighter variant of the model for faster forecasting. Because our models are significantly more proactive in identifying trend changes, this has improved forecasting, especially in long-range predictions and after the peak of an infection wave, as they were quicker to adapt to scenarios after these peaks in reported deaths. Assuming reported cases were under-reported greatly benefited the model in its stability, and modelling retroactively-added data (due to the “hot” nature of the data used) had a negligible impact on performance.
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spelling pubmed-95336372022-10-05 A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave da Costa Avelar, Pedro Henrique del Coco, Natalia Lamb, Luis C. Tsoka, Sophia Cardoso-Silva, Jonathan Healthcare Analytics Article Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty. At this early stage of an epidemic, where no vaccine or medical treatment is in sight, algorithmic prediction can become a powerful tool to inform local policymaking. However, when we replicated one prominent epidemiological model to inform health authorities in a region in the south of Brazil, we found that this model relied too heavily on manually predetermined covariates and was too reactive to changes in data trends. Our four proposed models access data of both daily reported deaths and infections as well as take into account missing data (e.g., the under-reporting of cases) more explicitly, with two of the proposed versions also attempting to model the delay in test reporting. We simulated weekly forecasting of deaths from the period from 31/05/2020 until 31/01/2021, with first week data being used as a cold-start to the algorithm, after which we use a lighter variant of the model for faster forecasting. Because our models are significantly more proactive in identifying trend changes, this has improved forecasting, especially in long-range predictions and after the peak of an infection wave, as they were quicker to adapt to scenarios after these peaks in reported deaths. Assuming reported cases were under-reported greatly benefited the model in its stability, and modelling retroactively-added data (due to the “hot” nature of the data used) had a negligible impact on performance. The Author(s). Published by Elsevier Inc. 2022-11 2022-10-05 /pmc/articles/PMC9533637/ /pubmed/37520620 http://dx.doi.org/10.1016/j.health.2022.100115 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
da Costa Avelar, Pedro Henrique
del Coco, Natalia
Lamb, Luis C.
Tsoka, Sophia
Cardoso-Silva, Jonathan
A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
title A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
title_full A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
title_fullStr A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
title_full_unstemmed A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
title_short A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
title_sort bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533637/
https://www.ncbi.nlm.nih.gov/pubmed/37520620
http://dx.doi.org/10.1016/j.health.2022.100115
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