Generation of a VeroE6 Pgp gene knock out cell line and its use in SARS-CoV-2 antiviral study

Vero cells are widely used for antiviral tests and virology research for SARS-CoV-2 as well as viruses from various other families. However, Vero cells generally express high levels of multi-drug resistance 1 (MDR1) or Pgp protein, the efflux transporter of foreign substances including many antivira...

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Detalles Bibliográficos
Autores principales: Zhu, Yuao, Binder, Joe, Yurgelonis, Irina, Rai, Devendra K., Lazarro, Sarah, Costales, Chester, Kobylarz, Keith, McMonagle, Patricia, Steppan, Claire M., Aschenbrenner, Lisa, Anderson, Annaliesa S., Cardin, Rhonda D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533647/
https://www.ncbi.nlm.nih.gov/pubmed/36208677
http://dx.doi.org/10.1016/j.antiviral.2022.105429

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