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Fractionated irradiation of MCF7 breast cancer cells rewires a gene regulatory circuit towards a treatment‐resistant stemness phenotype

Radiotherapy is the standard of care for breast cancer. However, surviving radioresistant cells can repopulate following treatment and provoke relapse. Better understanding of the molecular mechanisms of radiation resistance may help to improve treatment of radioresistant tumours. To emulate radiati...

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Detalles Bibliográficos
Autores principales: Inalegwu, Auchi, Cuypers, Bart, Claesen, Jürgen, Janssen, Ann, Coolkens, Amelie, Baatout, Sarah, Laukens, Kris, De Vos, Winnok H., Quintens, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533694/
https://www.ncbi.nlm.nih.gov/pubmed/35579852
http://dx.doi.org/10.1002/1878-0261.13226