Dosage comparison of Congo Basin and West African strains of monkeypox virus using a prairie dog animal model of systemic orthopoxvirus disease

The prairie dog is valuable for the study of monkeypox virus (MPXV) virulence and closely resembles human systemic orthopoxvirus disease. Herein, we utilize a variable dose intranasal challenge with approximately 10(3), 10(4), 10(5), and 10(6) PFU for each clade to further characterize virulence dif...

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Detalles Bibliográficos
Autores principales: Hutson, Christina L., Carroll, Darin S., Self, Joshua, Weiss, Sonja, Hughes, Christine M., Braden, Zachary, Olson, Victoria A., Smith, Scott K., Karem, Kevin L., Regnery, Russell L., Damon, Inger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533845/
https://www.ncbi.nlm.nih.gov/pubmed/20374968
http://dx.doi.org/10.1016/j.virol.2010.03.012

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