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Clonal vaccinia virus grown in cell culture fully protects monkeys from lethal monkeypox challenge

The potential use of smallpox as an agent of bioterrorism has renewed interest in the development of a modern vaccine capable of replacing the standard Dryvax(®) vaccine. Vaccinia virus (ACAM2000), clonally isolated from Dryvax(®) and manufactured in cell culture, was tested for immunogenicity and p...

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Detalles Bibliográficos
Autores principales:	Marriott, Kathleen A., Parkinson, Christopher V., Morefield, Samantha I., Davenport, Robert, Nichols, Richard, Monath, Thomas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533847/ https://www.ncbi.nlm.nih.gov/pubmed/18077063 http://dx.doi.org/10.1016/j.vaccine.2007.10.063

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