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Virulence differences between monkeypox virus isolates from West Africa and the Congo basin

Studies indicate that West African and Congo basin isolates of monkeypox virus (MPXV) are genetically distinct. Here, we show Congo basin MPXV-ZAI-V79 is more virulent for cynomolgus monkeys as compared to presumed West African MPXV-COP-58. This finding may explain the lack of case-fatalities in the...

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Detalles Bibliográficos
Autores principales: Chen, Nanhai, Li, Guiyun, Liszewski, M. Kathryn, Atkinson, John P., Jahrling, Peter B., Feng, Zehua, Schriewer, Jill, Buck, Charles, Wang, Chunlin, Lefkowitz, Elliot J., Esposito, Joseph J., Harms, Tiara, Damon, Inger K., Roper, Rachel L., Upton, Chris, Buller, R. Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534023/
https://www.ncbi.nlm.nih.gov/pubmed/16023693
http://dx.doi.org/10.1016/j.virol.2005.05.030