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Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity

Since the first monkeypox (MPX) case was reported in humans in 1970, there have been several outbreaks of the disease. MPX is endemic in central and western Africa. MPX virus infection is confirmed using the conventional polymerase chain reaction, which detects the viral DNA in samples from the rash...

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Autores principales: Moyo, Enos, Musuka, Godfrey, Murewanhema, Grant, Moyo, Perseverance, Dzinamarira, Tafadzwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534167/
https://www.ncbi.nlm.nih.gov/pubmed/36007687
http://dx.doi.org/10.1016/j.ijid.2022.08.016
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author Moyo, Enos
Musuka, Godfrey
Murewanhema, Grant
Moyo, Perseverance
Dzinamarira, Tafadzwa
author_facet Moyo, Enos
Musuka, Godfrey
Murewanhema, Grant
Moyo, Perseverance
Dzinamarira, Tafadzwa
author_sort Moyo, Enos
collection PubMed
description Since the first monkeypox (MPX) case was reported in humans in 1970, there have been several outbreaks of the disease. MPX is endemic in central and western Africa. MPX virus infection is confirmed using the conventional polymerase chain reaction, which detects the viral DNA in samples from the rash. Of concern is that the current outbreak has affected five regions of the world. Although MPX confirmatory tests are available worldwide, there are concerns about Africa's capacity to diagnose and contain the disease. The challenges faced by Africa include a lack of adequate laboratory infrastructure and health care workers, weak disease surveillance systems, and a lack of MPX knowledge among health care workers and communities. These challenges can be addressed by mobilizing resources for MPX virus testing, strengthening surveillance systems, collaboration among countries, training health care workers, task shifting, and engaging communities.
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spelling pubmed-95341672022-10-07 Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity Moyo, Enos Musuka, Godfrey Murewanhema, Grant Moyo, Perseverance Dzinamarira, Tafadzwa Int J Infect Dis Perspective Since the first monkeypox (MPX) case was reported in humans in 1970, there have been several outbreaks of the disease. MPX is endemic in central and western Africa. MPX virus infection is confirmed using the conventional polymerase chain reaction, which detects the viral DNA in samples from the rash. Of concern is that the current outbreak has affected five regions of the world. Although MPX confirmatory tests are available worldwide, there are concerns about Africa's capacity to diagnose and contain the disease. The challenges faced by Africa include a lack of adequate laboratory infrastructure and health care workers, weak disease surveillance systems, and a lack of MPX knowledge among health care workers and communities. These challenges can be addressed by mobilizing resources for MPX virus testing, strengthening surveillance systems, collaboration among countries, training health care workers, task shifting, and engaging communities. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022-10 2022-08-22 /pmc/articles/PMC9534167/ /pubmed/36007687 http://dx.doi.org/10.1016/j.ijid.2022.08.016 Text en © 2022 The Author(s) Elsevier has created a Monkeypox Information Center (https://www.elsevier.com/connect/monkeypox-information-center) in response to the declared public health emergency of international concern, with free information in English on the monkeypox virus. The Monkeypox Information Center is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its monkeypox related research that is available on the Monkeypox Information Center - including this research content - immediately available in publicly funded repositories, with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the Monkeypox Information Center remains active.
spellingShingle Perspective
Moyo, Enos
Musuka, Godfrey
Murewanhema, Grant
Moyo, Perseverance
Dzinamarira, Tafadzwa
Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_full Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_fullStr Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_full_unstemmed Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_short Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_sort monkeypox outbreak: a perspective on africa's diagnostic and containment capacity
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534167/
https://www.ncbi.nlm.nih.gov/pubmed/36007687
http://dx.doi.org/10.1016/j.ijid.2022.08.016
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