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Low-intensity exercise combined with sodium valproate attenuates kainic acid-induced seizures and associated co-morbidities by inhibiting NF-κB signaling in mice

Sodium valproate (VPA) is a broad-spectrum anticonvulsant that is effective both in adults and children suffering from epilepsy, but it causes psychiatric and behavioral side effects in patients with epilepsy. In addition, 30% of patients with epilepsy develop resistance to VPA. At present, regular...

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Detalles Bibliográficos
Autores principales: Jia, Yuxiang, Tang, Lele, Yao, Yu, Zhuo, Limin, Qu, Dongxiao, Chen, Xingxing, Ji, Yonghua, Tao, Jie, Zhu, Yudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534325/
https://www.ncbi.nlm.nih.gov/pubmed/36212646
http://dx.doi.org/10.3389/fneur.2022.993405