Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis

Bile acids (BAs) are complex and incompletely understood enterohepatic-derived hormones that control whole-body metabolism. Here, we profiled postprandial BAs in the liver, feces, and plasma of 360 chow- or high-fat-diet-fed BXD male mice and demonstrated that both genetics and diet strongly influen...

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Detalles Bibliográficos
Autores principales: Li, Hao, Perino, Alessia, Huang, Qingyao, Von Alvensleben, Giacomo V.G., Banaei-Esfahani, Amir, Velazquez-Villegas, Laura A., Gariani, Karim, Korbelius, Melanie, Bou Sleiman, Maroun, Imbach, Jéromine, Sun, Yu, Li, Xiaoxu, Bachmann, Alexis, Goeminne, Ludger J.E., Gallart-Ayala, Hector, Williams, Evan G., Ivanisevic, Julijana, Auwerx, Johan, Schoonjans, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534359/
https://www.ncbi.nlm.nih.gov/pubmed/36099916
http://dx.doi.org/10.1016/j.cmet.2022.08.015

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