Generation of SARS-CoV-2 Mouse Model by Transient Expression of the Human ACE2 Gene Mediated by Intranasal Administration of AAV-hACE2

One of the most important steps in the development of drugs and vaccines against a new coronavirus infection is their testing on a relevant animal model. The laboratory mouse, with well-studied immunology, is the preferred mammalian model in experimental medicine. However, mice are not susceptible t...

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Detalles Bibliográficos
Autores principales: Glazkova, D. V., Bogoslovskaya, E. V., Urusov, F. A., Kartashova, N. P., Glubokova, E. A., Gracheva, A. V., Faizuloev, E. B., Trunova, G. V., Khokhlova, V. A., Bezborodova, O. A., Pankratov, A. A., Leneva, I. A., Shipulin, G. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Virial Infections: Replication and Pathogenesis Mechanisms to Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534474/
https://www.ncbi.nlm.nih.gov/pubmed/36217340
http://dx.doi.org/10.1134/S0026893322050065

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