Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody

In this study, by characterizing several human monoclonal antibodies (mAbs) isolated from single B cells of the COVID-19–recovered individuals in India who experienced ancestral Wuhan strain (WA.1) of SARS-CoV-2 during early stages of the pandemic, we found a receptor binding domain (RBD)–specific m...

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Detalles Bibliográficos
Autores principales: Kumar, Sanjeev, Patel, Anamika, Lai, Lilin, Chakravarthy, Chennareddy, Valanparambil, Rajesh, Reddy, Elluri Seetharami, Gottimukkala, Kamalvishnu, Davis-Gardner, Meredith E., Edara, Venkata Viswanadh, Linderman, Susanne, Nayak, Kaustuv, Dixit, Kritika, Sharma, Pragati, Bajpai, Prashant, Singh, Vanshika, Frank, Filipp, Cheedarla, Narayanaiah, Verkerke, Hans P., Neish, Andrew S., Roback, John D., Mantus, Grace, Goel, Pawan Kumar, Rahi, Manju, Davis, Carl W., Wrammert, Jens, Godbole, Sucheta, Henry, Amy R., Douek, Daniel C., Suthar, Mehul S., Ahmed, Rafi, Ortlund, Eric, Sharma, Amit, Murali-Krishna, Kaja, Chandele, Anmol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534492/
https://www.ncbi.nlm.nih.gov/pubmed/36197988
http://dx.doi.org/10.1126/sciadv.add2032

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