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Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow

Iron is mostly devoted to the hemoglobinization of erythrocytes for oxygen transport. However, emerging evidence points to a broader role for the metal in hematopoiesis, including the formation of the immune system. Iron availability in mammalian cells is controlled by iron-regulatory protein 1 (IRP...

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Detalles Bibliográficos
Autores principales: Bonadonna, Michael, Altamura, Sandro, Tybl, Elisabeth, Palais, Gael, Qatato, Maria, Polycarpou-Schwarz, Maria, Schneider, Martin, Kalk, Christina, Rüdiger, Wibke, Ertl, Alina, Anstee, Natasha, Bogeska, Ruzhica, Helm, Dominic, Milsom, Michael D., Galy, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534496/
https://www.ncbi.nlm.nih.gov/pubmed/36197975
http://dx.doi.org/10.1126/sciadv.abq4469