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Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow
Iron is mostly devoted to the hemoglobinization of erythrocytes for oxygen transport. However, emerging evidence points to a broader role for the metal in hematopoiesis, including the formation of the immune system. Iron availability in mammalian cells is controlled by iron-regulatory protein 1 (IRP...
Autores principales: | Bonadonna, Michael, Altamura, Sandro, Tybl, Elisabeth, Palais, Gael, Qatato, Maria, Polycarpou-Schwarz, Maria, Schneider, Martin, Kalk, Christina, Rüdiger, Wibke, Ertl, Alina, Anstee, Natasha, Bogeska, Ruzhica, Helm, Dominic, Milsom, Michael D., Galy, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534496/ https://www.ncbi.nlm.nih.gov/pubmed/36197975 http://dx.doi.org/10.1126/sciadv.abq4469 |
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