A unique biomimetic modification endows polyetherketoneketone scaffold with osteoinductivity by activating cAMP/PKA signaling pathway

Osteoinductivity of a biomaterial scaffold can notably enhance the bone healing performance. In this study, we developed a biomimetic and hierarchically porous polyetherketoneketone (PEKK) scaffold with unique osteoinductivity using a combined surface treatment strategy of a sulfonated process and a...

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Detalles Bibliográficos
Autores principales: Yuan, Bo, Zhang, Yuxiang, Zhao, Rui, Lin, Hai, Yang, Xiao, Zhu, Xiangdong, Zhang, Kai, Mikos, Antonios G., Zhang, Xingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534509/
https://www.ncbi.nlm.nih.gov/pubmed/36197987
http://dx.doi.org/10.1126/sciadv.abq7116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534509/
https://www.ncbi.nlm.nih.gov/pubmed/36197987
http://dx.doi.org/10.1126/sciadv.abq7116

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