Critical role of lncEPAT in coupling dysregulated EGFR pathway and histone H2A deubiquitination during glioblastoma tumorigenesis

Histone 2A (H2A) monoubiquitination is a fundamental epigenetics mechanism of gene expression, which plays a critical role in regulating cell fate. However, it is unknown if H2A ubiquitination is involved in EGFR-driven tumorigenesis. In the current study, we have characterized a previously unidenti...

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Detalles Bibliográficos
Autores principales: Li, Linlin, Zhou, Aidong, Wei, Yanjun, Liu, Feng, Li, Peng, Fang, Runping, Ma, Li, Zhang, Sicong, Wang, Longqiang, Liu, Jinze, Richard, Hope T., Chen, Yiwen, Wang, Hengbin, Huang, Suyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534510/
https://www.ncbi.nlm.nih.gov/pubmed/36197973
http://dx.doi.org/10.1126/sciadv.abn2571

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