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Plasma iron controls neutrophil production and function

Low plasma iron (hypoferremia) induced by hepcidin is a conserved inflammatory response that protects against infections but inhibits erythropoiesis. How hypoferremia influences leukocytogenesis is unclear. Using proteomic data, we predicted that neutrophil production would be profoundly more iron-d...

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Detalles Bibliográficos
Autores principales: Frost, Joe N., Wideman, Sarah K., Preston, Alexandra E., Teh, Megan R., Ai, Zhichao, Wang, Lihui, Cross, Amy, White, Natasha, Yazicioglu, Yavuz, Bonadonna, Michael, Clarke, Alexander J., Armitage, Andrew E., Galy, Bruno, Udalova, Irina A., Drakesmith, Hal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534512/
https://www.ncbi.nlm.nih.gov/pubmed/36197985
http://dx.doi.org/10.1126/sciadv.abq5384