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Antioxidant Effect and Acute Oral Toxicity of Hot Springs

According to the research, there are many illnesses for which therapeutic mineral hot springs are employed as an alternative. Its physicochemical characteristics have a substantial body of evidence. The in vivo antioxidant effect of Mosul's hot springs in Iraq has been investigated in the curre...

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Autores principales: Hakeem, Israa J., Zewudie, Gashaw Tadele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534612/
https://www.ncbi.nlm.nih.gov/pubmed/36210965
http://dx.doi.org/10.1155/2022/4200824
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author Hakeem, Israa J.
Zewudie, Gashaw Tadele
author_facet Hakeem, Israa J.
Zewudie, Gashaw Tadele
author_sort Hakeem, Israa J.
collection PubMed
description According to the research, there are many illnesses for which therapeutic mineral hot springs are employed as an alternative. Its physicochemical characteristics have a substantial body of evidence. The in vivo antioxidant effect of Mosul's hot springs in Iraq has been investigated in the current investigation. An experimental design for toxicity, a control group, and a study group were created. In addition, in vivo antioxidant effect of the hot springs of Mosul, Iraq, has been studied by the lipid antiperoxidation method with (p < 0.05), in vitro by the free radical scavenging method (DPPH) for its complexing capacity of hot springs. In acute oral toxicity in vivo at fixed doses, looking for signs and symptoms of toxicity, there are no signs of intoxication or significant changes in the biochemical analysis (blood count). And, it was discovered that the variances are substantial. The animal was necropsied, and hematological and biochemical parameters were determined, as well as the organs' histological processing at the study's conclusion. It was found that the thermal waters from Mosul, Iraq, are medicinal mineral waters, chlorinated, sodium, and sulfated, nontoxic and have an antioxidant effect. With the help of the research's findings, it is hoped to provide scientific support for knowledge that, when made public, encourages the development of Mosul's hot springs as a safe and environmentally friendly tourist destination. With the results of this research, the parameters were presented with their mean and standard deviation statistics, promoting the ecological and sanitary tourism development of the Mosul hot springs, which will generate more significant income for the population, therefore growth in the region.
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spelling pubmed-95346122022-10-06 Antioxidant Effect and Acute Oral Toxicity of Hot Springs Hakeem, Israa J. Zewudie, Gashaw Tadele Comput Intell Neurosci Research Article According to the research, there are many illnesses for which therapeutic mineral hot springs are employed as an alternative. Its physicochemical characteristics have a substantial body of evidence. The in vivo antioxidant effect of Mosul's hot springs in Iraq has been investigated in the current investigation. An experimental design for toxicity, a control group, and a study group were created. In addition, in vivo antioxidant effect of the hot springs of Mosul, Iraq, has been studied by the lipid antiperoxidation method with (p < 0.05), in vitro by the free radical scavenging method (DPPH) for its complexing capacity of hot springs. In acute oral toxicity in vivo at fixed doses, looking for signs and symptoms of toxicity, there are no signs of intoxication or significant changes in the biochemical analysis (blood count). And, it was discovered that the variances are substantial. The animal was necropsied, and hematological and biochemical parameters were determined, as well as the organs' histological processing at the study's conclusion. It was found that the thermal waters from Mosul, Iraq, are medicinal mineral waters, chlorinated, sodium, and sulfated, nontoxic and have an antioxidant effect. With the help of the research's findings, it is hoped to provide scientific support for knowledge that, when made public, encourages the development of Mosul's hot springs as a safe and environmentally friendly tourist destination. With the results of this research, the parameters were presented with their mean and standard deviation statistics, promoting the ecological and sanitary tourism development of the Mosul hot springs, which will generate more significant income for the population, therefore growth in the region. Hindawi 2022-09-28 /pmc/articles/PMC9534612/ /pubmed/36210965 http://dx.doi.org/10.1155/2022/4200824 Text en Copyright © 2022 Israa J. Hakeem and Gashaw Tadele Zewudie. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Hakeem, Israa J.
Zewudie, Gashaw Tadele
Antioxidant Effect and Acute Oral Toxicity of Hot Springs
title Antioxidant Effect and Acute Oral Toxicity of Hot Springs
title_full Antioxidant Effect and Acute Oral Toxicity of Hot Springs
title_fullStr Antioxidant Effect and Acute Oral Toxicity of Hot Springs
title_full_unstemmed Antioxidant Effect and Acute Oral Toxicity of Hot Springs
title_short Antioxidant Effect and Acute Oral Toxicity of Hot Springs
title_sort antioxidant effect and acute oral toxicity of hot springs
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534612/
https://www.ncbi.nlm.nih.gov/pubmed/36210965
http://dx.doi.org/10.1155/2022/4200824
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