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A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes
Environmental cues influence the highly dynamic morphology of microglia. Strategies to characterize these changes usually involve user-selected morphometric features, which preclude the identification of a spectrum of context-dependent morphological phenotypes. Here we develop MorphOMICs, a topologi...
Autores principales: | Colombo, Gloria, Cubero, Ryan John A., Kanari, Lida, Venturino, Alessandro, Schulz, Rouven, Scolamiero, Martina, Agerberg, Jens, Mathys, Hansruedi, Tsai, Li-Huei, Chachólski, Wojciech, Hess, Kathryn, Siegert, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534764/ https://www.ncbi.nlm.nih.gov/pubmed/36180790 http://dx.doi.org/10.1038/s41593-022-01167-6 |
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