Cargando…

A comparative characterization of SARS-CoV-2-specific T cells induced by mRNA or inactive virus COVID-19 vaccines

Unlike mRNA vaccines based only on the spike protein, inactivated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines should induce a diversified T cell response recognizing distinct structural proteins. Here, we perform a comparative analysis of SARS-CoV-2-specific T cells in heal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Joey Ming Er, Hang, Shou Kit, Hariharaputran, Smrithi, Chia, Adeline, Tan, Nicole, Lee, Eng Sing, Chng, Edwin, Lim, Poh Lian, Young, Barnaby E., Lye, David Chien, Le Bert, Nina, Bertoletti, Antonio, Tan, Anthony T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534788/ https://www.ncbi.nlm.nih.gov/pubmed/36257326 http://dx.doi.org/10.1016/j.xcrm.2022.100793

Ejemplares similares

SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8(+) and CD4(+) T cells of broad specificity
por: Lim, Joey Ming Er, et al.
Publicado: (2022)

Favorable vaccine-induced SARS-CoV-2–specific T cell response profile in patients undergoing immune-modifying therapies
por: Qui, Martin, et al.
Publicado: (2022)

Protocol to detect antigen-specific nasal-resident T cells in humans
por: Lim, Joey Ming Er, et al.
Publicado: (2023)

Protection from infection or disease? Re-evaluating the broad immunogenicity of inactivated SARS-CoV-2 vaccines
por: Tan, Anthony T., et al.
Publicado: (2022)

Prevalence and functional profile of SARS-CoV-2 T cells in asymptomatic Kenyan adults
por: Samandari, Taraz, et al.
Publicado: (2023)

The Characteristics of Patients Associated With High Caregiver Burden in Parkinson's Disease in Singapore
por: Tan, Mark M. J., et al.
Publicado: (2019)

BNT162b2 vaccine induced variant-specific immunity, safety and risk of Omicron breakthrough infection in children aged 5 to 11 years: a cohort study
por: Yung, Chee Fu, et al.
Publicado: (2023)

HBV-HCC treatment with mRNA electroporated HBV-TCR T cells
por: Tan, Anthony T, et al.
Publicado: (2021)

Spike-specific humoral and cellular immune responses after COVID-19 mRNA vaccination in patients with cirrhosis: A prospective single center study
por: Iavarone, Massimo, et al.
Publicado: (2023)

Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
por: Tan, Anthony T., et al.
Publicado: (2021)

Differential immunogenicity of homologous versus heterologous boost in Ad26.COV2.S vaccine recipients
por: Khoo, Nicholas Kim Huat, et al.
Publicado: (2022)

Passive, yet not inactive: robotic exoskeleton walking increases cortical activation dependent on task
por: Peters, Sue, et al.
Publicado: (2020)

Cross-Reactivity and Anti-viral Function of Dengue Capsid and NS3-Specific Memory T Cells Toward Zika Virus
por: Lim, Mei Qiu, et al.
Publicado: (2018)

COVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in 73 608 Patients With Cancer and 621 475 Matched Controls in Singapore: A Nationwide Cohort Study
por: Tan, Wei Chong, et al.
Publicado: (2023)

Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine
por: Goh, Yun Shan, et al.
Publicado: (2022)

Real-world effectiveness of nirmatrelvir/ritonavir against COVID-19 hospitalisations and severe COVID-19 in community-dwelling elderly Singaporeans during Omicron BA.2, BA.4/5 and XBB transmission
por: Wee, Liang En, et al.
Publicado: (2023)

The T-cell response to SARS-CoV-2: kinetic and quantitative aspects and the case for their protective role
por: Bertoletti, Antonio, et al.
Publicado: (2021)

SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic
por: Bertoletti, Antonio, et al.
Publicado: (2022)

Act Early and at the Right Location: SARS-CoV-2 T Cell Kinetics and Tissue Localization
por: Bertoletti, Antonio, et al.
Publicado: (2022)

Statin use is associated with lower disease severity in COVID-19 infection
por: Tan, Wilnard Y. T., et al.
Publicado: (2020)

Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection
por: Le Bert, Nina, et al.
Publicado: (2021)

Predictors for development of critical illness amongst older adults with COVID-19: Beyond age to age-associated factors
por: Lim, Jun Pei, et al.
Publicado: (2021)

Deterministic Tractography of the Nigrostriatal-Nigropallidal Pathway in Parkinson’s Disease
por: Tan, Wen-Qi, et al.
Publicado: (2015)

SARS-CoV-2-specific T cells in infection and vaccination
por: Bertoletti, Antonio, et al.
Publicado: (2021)

Comparative effectiveness of 3 or 4 doses of mRNA and inactivated whole-virus vaccines against COVID-19 infection, hospitalization and severe outcomes among elderly in Singapore
por: Tan, Celine Y., et al.
Publicado: (2022)

High Diagnostic Utility Incorporating a Targeted Neurodegeneration Gene Panel With MRI Brain Diagnostic Algorithms in Patients With Young-Onset Cognitive Impairment With Leukodystrophy
por: Chen, Zhiyong, et al.
Publicado: (2021)

Course Review: Doctors Academy Basic Sciences and Clinical Application for the Membership of the Royal College of Surgeons Part A Course
por: Eng, Khemerin, et al.
Publicado: (2021)

Risk factors for early TB treatment interruption among newly diagnosed patients in Malaysia
por: Suliman, Qudsiah, et al.
Publicado: (2022)

Heterosexual men who patronise entertainment establishments versus brothels in an Asian urban setting – which group practises riskier sexual behaviours?
por: Lim, Raymond Boon Tar, et al.
Publicado: (2015)

YouTube Video Educational Package Increased Acceptance of Antibiotic Clinical Decision Support System Recommendations
por: Heng, Shi Thong, et al.
Publicado: (2017)

Remote Prescription During Pandemic: Challenges and Solutions
por: Lim, Ee-Chien, et al.
Publicado: (2021)

Lack of detail in population-level data impedes analysis of SARS-CoV-2 variants of concern and clinical outcomes
por: Ong, Sean Wei Xiang, et al.
Publicado: (2021)

Improving medication adherence with adjuvant aromatase inhibitor in women with breast cancer: A randomised controlled trial to evaluate the effect of short message service (SMS) reminder
por: Tan, Eng Hooi, et al.
Publicado: (2020)

Beliefs about medicines and adherence in women with breast cancer on adjuvant endocrine therapy
por: Tan, Eng Hooi, et al.
Publicado: (2021)

Intermediate C9orf72 alleles in neurological disorders: does size really matter?
por: Ng, Adeline S L, et al.
Publicado: (2017)

Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection
por: Ng, Oi-Wing, et al.
Publicado: (2016)

Early T cell and binding antibody responses are associated with COVID-19 RNA vaccine efficacy onset
por: Kalimuddin, Shirin, et al.
Publicado: (2021)

Implementing healthy food environment policies in New Zealand: nine years of inaction
por: Mackay, Sally, et al.
Publicado: (2022)

Derivation and validation of an accurate estimation of CD4 counts from the absolute lymphocyte count in virologically suppressed and immunologically reconstituted HIV infected adults
por: Young, Barnaby, et al.
Publicado: (2015)

Real-time knowledge-based fuzzy logic model for soft tissue deformation
por: Tan, Joey Sing Yee, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ovjbqkbgegp5hgorrc04om8asr