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Clusterin negatively modulates mechanical stress-mediated ligamentum flavum hypertrophy through TGF-β1 signaling

Ligamentum flavum hypertrophy (LFH) is a major cause of lumbar spinal canal stenosis (LSCS). The pathomechanisms for LFH have not been fully elucidated. Isobaric tags for relative and absolute quantitation (iTRAQ) technology, proteomics assessments of human ligamentum flavum (LF), and successive ass...

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Detalles Bibliográficos
Autores principales:	Liu, Chunlei, Li, Peng, Ao, Xiang, Lian, Zhengnan, Liu, Jie, Li, Chenglong, Huang, Minjun, Wang, Liang, Zhang, Zhongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534863/ https://www.ncbi.nlm.nih.gov/pubmed/36131026 http://dx.doi.org/10.1038/s12276-022-00849-2

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