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3D-printed microrobots from design to translation

Microrobots have attracted the attention of scientists owing to their unique features to accomplish tasks in hard-to-reach sites in the human body. Microrobots can be precisely actuated and maneuvered individually or in a swarm for cargo delivery, sampling, surgery, and imaging applications. In addi...

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Autores principales: Dabbagh, Sajjad Rahmani, Sarabi, Misagh Rezapour, Birtek, Mehmet Tugrul, Seyfi, Siamak, Sitti, Metin, Tasoglu, Savas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534872/
https://www.ncbi.nlm.nih.gov/pubmed/36198675
http://dx.doi.org/10.1038/s41467-022-33409-3
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author Dabbagh, Sajjad Rahmani
Sarabi, Misagh Rezapour
Birtek, Mehmet Tugrul
Seyfi, Siamak
Sitti, Metin
Tasoglu, Savas
author_facet Dabbagh, Sajjad Rahmani
Sarabi, Misagh Rezapour
Birtek, Mehmet Tugrul
Seyfi, Siamak
Sitti, Metin
Tasoglu, Savas
author_sort Dabbagh, Sajjad Rahmani
collection PubMed
description Microrobots have attracted the attention of scientists owing to their unique features to accomplish tasks in hard-to-reach sites in the human body. Microrobots can be precisely actuated and maneuvered individually or in a swarm for cargo delivery, sampling, surgery, and imaging applications. In addition, microrobots have found applications in the environmental sector (e.g., water treatment). Besides, recent advancements of three-dimensional (3D) printers have enabled the high-resolution fabrication of microrobots with a faster design-production turnaround time for users with limited micromanufacturing skills. Here, the latest end applications of 3D printed microrobots are reviewed (ranging from environmental to biomedical applications) along with a brief discussion over the feasible actuation methods (e.g., on- and off-board), and practical 3D printing technologies for microrobot fabrication. In addition, as a future perspective, we discussed the potential advantages of integration of microrobots with smart materials, and conceivable benefits of implementation of artificial intelligence (AI), as well as physical intelligence (PI). Moreover, in order to facilitate bench-to-bedside translation of microrobots, current challenges impeding clinical translation of microrobots are elaborated, including entry obstacles (e.g., immune system attacks) and cumbersome standard test procedures to ensure biocompatibility.
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spelling pubmed-95348722022-10-07 3D-printed microrobots from design to translation Dabbagh, Sajjad Rahmani Sarabi, Misagh Rezapour Birtek, Mehmet Tugrul Seyfi, Siamak Sitti, Metin Tasoglu, Savas Nat Commun Review Article Microrobots have attracted the attention of scientists owing to their unique features to accomplish tasks in hard-to-reach sites in the human body. Microrobots can be precisely actuated and maneuvered individually or in a swarm for cargo delivery, sampling, surgery, and imaging applications. In addition, microrobots have found applications in the environmental sector (e.g., water treatment). Besides, recent advancements of three-dimensional (3D) printers have enabled the high-resolution fabrication of microrobots with a faster design-production turnaround time for users with limited micromanufacturing skills. Here, the latest end applications of 3D printed microrobots are reviewed (ranging from environmental to biomedical applications) along with a brief discussion over the feasible actuation methods (e.g., on- and off-board), and practical 3D printing technologies for microrobot fabrication. In addition, as a future perspective, we discussed the potential advantages of integration of microrobots with smart materials, and conceivable benefits of implementation of artificial intelligence (AI), as well as physical intelligence (PI). Moreover, in order to facilitate bench-to-bedside translation of microrobots, current challenges impeding clinical translation of microrobots are elaborated, including entry obstacles (e.g., immune system attacks) and cumbersome standard test procedures to ensure biocompatibility. Nature Publishing Group UK 2022-10-05 /pmc/articles/PMC9534872/ /pubmed/36198675 http://dx.doi.org/10.1038/s41467-022-33409-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Dabbagh, Sajjad Rahmani
Sarabi, Misagh Rezapour
Birtek, Mehmet Tugrul
Seyfi, Siamak
Sitti, Metin
Tasoglu, Savas
3D-printed microrobots from design to translation
title 3D-printed microrobots from design to translation
title_full 3D-printed microrobots from design to translation
title_fullStr 3D-printed microrobots from design to translation
title_full_unstemmed 3D-printed microrobots from design to translation
title_short 3D-printed microrobots from design to translation
title_sort 3d-printed microrobots from design to translation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534872/
https://www.ncbi.nlm.nih.gov/pubmed/36198675
http://dx.doi.org/10.1038/s41467-022-33409-3
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