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Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1

Extracranial arteriovenous malformations (AVMs) are characterized by anomalous arterial-to-venous connections, aberrant angiogenesis, local inflammation and hypoxia, and disorganized histological architecture; however, the precise molecular perturbations leading to this phenotype remain elusive. We...

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Detalles Bibliográficos
Autores principales: Wei, Ting, Richter, Gresham T., Zhang, Haihong, Sun, Ravi W., Smith, Conor H., Strub, Graham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534897/
https://www.ncbi.nlm.nih.gov/pubmed/36198763
http://dx.doi.org/10.1038/s41598-022-21217-0