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Complex genomic patterns of abasic sites in mammalian DNA revealed by a high-resolution SSiNGLe-AP method

DNA damage plays a critical role in biology and diseases; however, how different types of DNA lesions affect cellular functions is far from clear mostly due to the paucity of high-resolution methods that can map their locations in complex genomes, such as those of mammals. Here, we present the devel...

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Detalles Bibliográficos
Autores principales: Cai, Ye, Cao, Huifen, Wang, Fang, Zhang, Yufei, Kapranov, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534904/
https://www.ncbi.nlm.nih.gov/pubmed/36198706
http://dx.doi.org/10.1038/s41467-022-33594-1