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A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022)
Early Organogenesis In vitro culture of embryos is a useful tool to explore the mysteries of life. As the natural platform for embryo development, the uterus inspires the building of in vitro culture conditions. In article number 2202282 by Qi Gu, Hongmei Wang, Shutao Wang, and co‐workers, particula...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534943/ http://dx.doi.org/10.1002/advs.202270180 |
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author | Gu, Zhen Guo, Jia Zhai, Jinglei Feng, Guihai Wang, Xianning Gao, Zili Li, Kai Ji, Shen Wang, Leyun Xu, Yanhong Chen, Xi Wang, Yiming Guo, Shanshan Yang, Man Li, Linlin Han, Hua Jiang, Liyuan Wen, Yongqiang Wang, Liu Hao, Jie Li, Wei Wang, Shutao Wang, Hongmei Gu, Qi |
author_facet | Gu, Zhen Guo, Jia Zhai, Jinglei Feng, Guihai Wang, Xianning Gao, Zili Li, Kai Ji, Shen Wang, Leyun Xu, Yanhong Chen, Xi Wang, Yiming Guo, Shanshan Yang, Man Li, Linlin Han, Hua Jiang, Liyuan Wen, Yongqiang Wang, Liu Hao, Jie Li, Wei Wang, Shutao Wang, Hongmei Gu, Qi |
author_sort | Gu, Zhen |
collection | PubMed |
description | Early Organogenesis In vitro culture of embryos is a useful tool to explore the mysteries of life. As the natural platform for embryo development, the uterus inspires the building of in vitro culture conditions. In article number 2202282 by Qi Gu, Hongmei Wang, Shutao Wang, and co‐workers, particularly designed collagen is grafted onto polydimethylsiloxane to simulate the moduli of the endometrium and uterine horn and the microstructure of the endometrium during mouse pregnancy. The uterus‐inspired niche microenvironment controls the migration and assembly of extraembryonic tissues, simulates embryo implantation, and ultimately promotes embryo development to early organogenesis. [Image: see text] |
format | Online Article Text |
id | pubmed-9534943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95349432022-10-11 A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) Gu, Zhen Guo, Jia Zhai, Jinglei Feng, Guihai Wang, Xianning Gao, Zili Li, Kai Ji, Shen Wang, Leyun Xu, Yanhong Chen, Xi Wang, Yiming Guo, Shanshan Yang, Man Li, Linlin Han, Hua Jiang, Liyuan Wen, Yongqiang Wang, Liu Hao, Jie Li, Wei Wang, Shutao Wang, Hongmei Gu, Qi Adv Sci (Weinh) Frontispiece Early Organogenesis In vitro culture of embryos is a useful tool to explore the mysteries of life. As the natural platform for embryo development, the uterus inspires the building of in vitro culture conditions. In article number 2202282 by Qi Gu, Hongmei Wang, Shutao Wang, and co‐workers, particularly designed collagen is grafted onto polydimethylsiloxane to simulate the moduli of the endometrium and uterine horn and the microstructure of the endometrium during mouse pregnancy. The uterus‐inspired niche microenvironment controls the migration and assembly of extraembryonic tissues, simulates embryo implantation, and ultimately promotes embryo development to early organogenesis. [Image: see text] John Wiley and Sons Inc. 2022-10-05 /pmc/articles/PMC9534943/ http://dx.doi.org/10.1002/advs.202270180 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Frontispiece Gu, Zhen Guo, Jia Zhai, Jinglei Feng, Guihai Wang, Xianning Gao, Zili Li, Kai Ji, Shen Wang, Leyun Xu, Yanhong Chen, Xi Wang, Yiming Guo, Shanshan Yang, Man Li, Linlin Han, Hua Jiang, Liyuan Wen, Yongqiang Wang, Liu Hao, Jie Li, Wei Wang, Shutao Wang, Hongmei Gu, Qi A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) |
title | A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) |
title_full | A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) |
title_fullStr | A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) |
title_full_unstemmed | A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) |
title_short | A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis (Adv. Sci. 28/2022) |
title_sort | uterus‐inspired niche drives blastocyst development to the early organogenesis (adv. sci. 28/2022) |
topic | Frontispiece |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534943/ http://dx.doi.org/10.1002/advs.202270180 |
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