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Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application

Fecal microbiota transplantation (FMT) has been proved to be an effective treatment for gastrointestinal disorders caused due to microbial disbalance. Nowadays, this approach is being used to treat extragastrointestinal conditions like metabolic and neurological disorders, which are considered to ha...

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Autores principales: Nigam, Manisha, Panwar, Abhaya Shikhar, Singh, Rahul Kunwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535080/
https://www.ncbi.nlm.nih.gov/pubmed/36212607
http://dx.doi.org/10.3389/fmedt.2022.961569
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author Nigam, Manisha
Panwar, Abhaya Shikhar
Singh, Rahul Kunwar
author_facet Nigam, Manisha
Panwar, Abhaya Shikhar
Singh, Rahul Kunwar
author_sort Nigam, Manisha
collection PubMed
description Fecal microbiota transplantation (FMT) has been proved to be an effective treatment for gastrointestinal disorders caused due to microbial disbalance. Nowadays, this approach is being used to treat extragastrointestinal conditions like metabolic and neurological disorders, which are considered to have their provenance in microbial dysbiosis in the intestine. Even though case studies and clinical trials have demonstrated the potential of FMT in treating a variety of ailments, safety and ethical concerns must be answered before the technique is widely used to the community's overall benefit. From this perspective, it is not unexpected that techniques for altering gut microbiota may represent a form of medication whose potential has not yet been thoroughly addressed. This review intends to gather data on recent developments in FMT and its safety, constraints, and ethical considerations.
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spelling pubmed-95350802022-10-07 Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application Nigam, Manisha Panwar, Abhaya Shikhar Singh, Rahul Kunwar Front Med Technol Medical Technology Fecal microbiota transplantation (FMT) has been proved to be an effective treatment for gastrointestinal disorders caused due to microbial disbalance. Nowadays, this approach is being used to treat extragastrointestinal conditions like metabolic and neurological disorders, which are considered to have their provenance in microbial dysbiosis in the intestine. Even though case studies and clinical trials have demonstrated the potential of FMT in treating a variety of ailments, safety and ethical concerns must be answered before the technique is widely used to the community's overall benefit. From this perspective, it is not unexpected that techniques for altering gut microbiota may represent a form of medication whose potential has not yet been thoroughly addressed. This review intends to gather data on recent developments in FMT and its safety, constraints, and ethical considerations. Frontiers Media S.A. 2022-09-22 /pmc/articles/PMC9535080/ /pubmed/36212607 http://dx.doi.org/10.3389/fmedt.2022.961569 Text en © 2022 Nigam, Panwar and Singh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medical Technology
Nigam, Manisha
Panwar, Abhaya Shikhar
Singh, Rahul Kunwar
Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application
title Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application
title_full Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application
title_fullStr Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application
title_full_unstemmed Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application
title_short Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application
title_sort orchestrating the fecal microbiota transplantation: current technological advancements and potential biomedical application
topic Medical Technology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535080/
https://www.ncbi.nlm.nih.gov/pubmed/36212607
http://dx.doi.org/10.3389/fmedt.2022.961569
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