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CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer

CXCL8 is an inflammatory chemokine elevated in the colorectal cancer (CRC) tumour microenvironment. CXCR2, the major receptor for CXCL8, is predominantly expressed by neutrophils. In the cancer setting, CXCL8 plays important roles in neutrophil chemotaxis, facilitating angiogenesis, invasion, and me...

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Detalles Bibliográficos
Autores principales: Pennel, Kathryn AF, Quinn, Jean A, Nixon, Colin, Inthagard, Jitwadee, van Wyk, Hester C, Chang, David, Rebus, Selma, Hay, Jennifer, Maka, Noori N, Roxburgh, Campbell SD, Horgan, Paul G, McMillan, Donald C, Park, James H, Roseweir, Antonia K, Steele, Colin W, Edwards, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535100/
https://www.ncbi.nlm.nih.gov/pubmed/35879507
http://dx.doi.org/10.1002/cjp2.290