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ATXN2-Mediated PI3K/AKT Activation Confers Gastric Cancer Chemoresistance and Attenuates CD8(+) T Cell Cytotoxicity
As one of the primary therapeutic choices, chemotherapy is widely adopted for progressive gastric cancer (GC), but the development of chemoresistance has limited chemotherapy efficacy and partly contributes to poor prognosis. Immunotherapy is increasingly being applied in the clinical treatment of G...
Autores principales: | Wang, Qi, Cao, Tianyu, Zhang, Xiaohui, Hui, Juan, Wang, Chen, Zhang, Wenyao, Wang, Pei, Zhou, Yun, Han, Shuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535133/ https://www.ncbi.nlm.nih.gov/pubmed/36213324 http://dx.doi.org/10.1155/2022/6863240 |
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