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Efficacy of bivalent CEACAM6/4-1BBL genetic vaccine combined with anti-PD1 antibody in MC38 tumor model of mice

We used mouse CRC cell line (MC38) to establish a heterotopic mouse model, and applied [(89)Zr]-labeled PD-L1 antibody KN035 for PET imaging. Attenuated Salmonella typhimurium 3261 was used as an anti-tumor vaccine, and the combined anti-tumor immunotherapy with bivalent genetic vaccine and anti-PD1...

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Detalles Bibliográficos
Autores principales:	Li, Yuzhen, Zhu, Xiaodan, You, Jianliang, Zhang, Baonan, Huang, Xiaona, Jin, Chunhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535276/ https://www.ncbi.nlm.nih.gov/pubmed/36212004 http://dx.doi.org/10.1016/j.heliyon.2022.e10775

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