A case of massive refractory diarrhea in a patient with COVID‐19

BACKGROUND: The new coronavirus disease (COVID‐19) causes gastrointestinal symptoms as well as respiratory symptoms. CASE PRESENTATION: A 60‐year‐old man was transferred with respiratory difficulty. He was diagnosed as having COVID‐19 and was intubated and placed on mechanical ventilation. He suffer...

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Autores principales: Shimizu, Kentaro, Hirata, Haruhiko, Tokuhira, Natsuko, Ueda, Akiko, Motooka, Daisuke, Nakamura, Shota, Ogura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535351/
https://www.ncbi.nlm.nih.gov/pubmed/36225723
http://dx.doi.org/10.1002/ams2.793
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author Shimizu, Kentaro
Hirata, Haruhiko
Tokuhira, Natsuko
Ueda, Akiko
Motooka, Daisuke
Nakamura, Shota
Ogura, Hiroshi
author_facet Shimizu, Kentaro
Hirata, Haruhiko
Tokuhira, Natsuko
Ueda, Akiko
Motooka, Daisuke
Nakamura, Shota
Ogura, Hiroshi
author_sort Shimizu, Kentaro
collection PubMed
description BACKGROUND: The new coronavirus disease (COVID‐19) causes gastrointestinal symptoms as well as respiratory symptoms. CASE PRESENTATION: A 60‐year‐old man was transferred with respiratory difficulty. He was diagnosed as having COVID‐19 and was intubated and placed on mechanical ventilation. He suffered from diarrhea from day 12 and produced a maximum of approximately 6,384 mL/day of watery diarrhea on day 21. He required massive transfusion. Adsorbents and pectin‐containing oligomeric formulas were administered, which decreased the amount of diarrhea. Fecal metagenomic analysis showed the proportions of the genera Enterococcus and Staphylococcus were the most dominate at the genus level. The proportion of Bacteroidetes was <1%. Thereafter, his diarrhea decreased to several times, and he was transferred to another ward on day 104. CONCLUSION: Therapy for intestinal complications as well as that for pneumonia might be important in treating COVID‐19.
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spelling pubmed-95353512022-10-11 A case of massive refractory diarrhea in a patient with COVID‐19 Shimizu, Kentaro Hirata, Haruhiko Tokuhira, Natsuko Ueda, Akiko Motooka, Daisuke Nakamura, Shota Ogura, Hiroshi Acute Med Surg Case Report BACKGROUND: The new coronavirus disease (COVID‐19) causes gastrointestinal symptoms as well as respiratory symptoms. CASE PRESENTATION: A 60‐year‐old man was transferred with respiratory difficulty. He was diagnosed as having COVID‐19 and was intubated and placed on mechanical ventilation. He suffered from diarrhea from day 12 and produced a maximum of approximately 6,384 mL/day of watery diarrhea on day 21. He required massive transfusion. Adsorbents and pectin‐containing oligomeric formulas were administered, which decreased the amount of diarrhea. Fecal metagenomic analysis showed the proportions of the genera Enterococcus and Staphylococcus were the most dominate at the genus level. The proportion of Bacteroidetes was <1%. Thereafter, his diarrhea decreased to several times, and he was transferred to another ward on day 104. CONCLUSION: Therapy for intestinal complications as well as that for pneumonia might be important in treating COVID‐19. John Wiley and Sons Inc. 2022-10-05 /pmc/articles/PMC9535351/ /pubmed/36225723 http://dx.doi.org/10.1002/ams2.793 Text en © 2022 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Shimizu, Kentaro
Hirata, Haruhiko
Tokuhira, Natsuko
Ueda, Akiko
Motooka, Daisuke
Nakamura, Shota
Ogura, Hiroshi
A case of massive refractory diarrhea in a patient with COVID‐19
title A case of massive refractory diarrhea in a patient with COVID‐19
title_full A case of massive refractory diarrhea in a patient with COVID‐19
title_fullStr A case of massive refractory diarrhea in a patient with COVID‐19
title_full_unstemmed A case of massive refractory diarrhea in a patient with COVID‐19
title_short A case of massive refractory diarrhea in a patient with COVID‐19
title_sort case of massive refractory diarrhea in a patient with covid‐19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535351/
https://www.ncbi.nlm.nih.gov/pubmed/36225723
http://dx.doi.org/10.1002/ams2.793
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