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Examining the diversity of structural motifs in fungal glycome

In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB). The monomeric and dimeric compositions of...

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Autores principales: Toukach, Philip V., Egorova, Ksenia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535381/
https://www.ncbi.nlm.nih.gov/pubmed/36249563
http://dx.doi.org/10.1016/j.csbj.2022.09.040
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author Toukach, Philip V.
Egorova, Ksenia S.
author_facet Toukach, Philip V.
Egorova, Ksenia S.
author_sort Toukach, Philip V.
collection PubMed
description In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB). The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed. The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi. It can also be useful for revealing specific glycosyltransferases active in a particular fungal species.
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spelling pubmed-95353812022-10-14 Examining the diversity of structural motifs in fungal glycome Toukach, Philip V. Egorova, Ksenia S. Comput Struct Biotechnol J Research Article In this paper, we present the results of a systematic statistical analysis of the fungal glycome in comparison with the prokaryotic and protistal glycomes as described in the scientific literature and presented in the Carbohydrate Structure Database (CSDB). The monomeric and dimeric compositions of glycans, their non-carbohydrate modifications, glycosidic linkages, sizes of structures, branching degree and net charge are assessed. The obtained information can help elucidating carbohydrate molecular markers for various fungal classes which, in its turn, can be demanded for the development of diagnostic tools and carbohydrate-based vaccines against pathogenic fungi. It can also be useful for revealing specific glycosyltransferases active in a particular fungal species. Research Network of Computational and Structural Biotechnology 2022-09-28 /pmc/articles/PMC9535381/ /pubmed/36249563 http://dx.doi.org/10.1016/j.csbj.2022.09.040 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Toukach, Philip V.
Egorova, Ksenia S.
Examining the diversity of structural motifs in fungal glycome
title Examining the diversity of structural motifs in fungal glycome
title_full Examining the diversity of structural motifs in fungal glycome
title_fullStr Examining the diversity of structural motifs in fungal glycome
title_full_unstemmed Examining the diversity of structural motifs in fungal glycome
title_short Examining the diversity of structural motifs in fungal glycome
title_sort examining the diversity of structural motifs in fungal glycome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535381/
https://www.ncbi.nlm.nih.gov/pubmed/36249563
http://dx.doi.org/10.1016/j.csbj.2022.09.040
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