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Wide local excision for Merkel cell carcinoma of the lower extremity: A case report

Primary Merkel cell carcinoma (MCC) is rare and wide local excision is the primary method of treatment. However, no consensus has been reached on the best surgical approach and research is currently limited. The choice of surgical method depends on the experience of the surgeon and the situation of...

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Autores principales: Zhang, Yong, Sun, Yan, Mo, Juefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535395/
https://www.ncbi.nlm.nih.gov/pubmed/36277148
http://dx.doi.org/10.3892/etm.2022.11636
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author Zhang, Yong
Sun, Yan
Mo, Juefei
author_facet Zhang, Yong
Sun, Yan
Mo, Juefei
author_sort Zhang, Yong
collection PubMed
description Primary Merkel cell carcinoma (MCC) is rare and wide local excision is the primary method of treatment. However, no consensus has been reached on the best surgical approach and research is currently limited. The choice of surgical method depends on the experience of the surgeon and the situation of the patient. In the present study, the clinical data of a single case of primary MCC that was treated with wide local excision in June 2019 were retrospectively analyzed and the associated literature was reviewed. The patient underwent complete resection of the tumor, which extended 2 cm from the outer edge of the nodule and reached the subcutaneous fat layer. The wound was closed with a tension-relieving suture. The stitches were removed 15 days following surgery and the wound had healed adequately. No recurrence occurred during 30 months of follow-up. However, further multi-center prospective randomized clinical trials are required for further investigation.
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spelling pubmed-95353952022-10-21 Wide local excision for Merkel cell carcinoma of the lower extremity: A case report Zhang, Yong Sun, Yan Mo, Juefei Exp Ther Med Case Report Primary Merkel cell carcinoma (MCC) is rare and wide local excision is the primary method of treatment. However, no consensus has been reached on the best surgical approach and research is currently limited. The choice of surgical method depends on the experience of the surgeon and the situation of the patient. In the present study, the clinical data of a single case of primary MCC that was treated with wide local excision in June 2019 were retrospectively analyzed and the associated literature was reviewed. The patient underwent complete resection of the tumor, which extended 2 cm from the outer edge of the nodule and reached the subcutaneous fat layer. The wound was closed with a tension-relieving suture. The stitches were removed 15 days following surgery and the wound had healed adequately. No recurrence occurred during 30 months of follow-up. However, further multi-center prospective randomized clinical trials are required for further investigation. D.A. Spandidos 2022-09-29 /pmc/articles/PMC9535395/ /pubmed/36277148 http://dx.doi.org/10.3892/etm.2022.11636 Text en Copyright: © Zhang et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Report
Zhang, Yong
Sun, Yan
Mo, Juefei
Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
title Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
title_full Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
title_fullStr Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
title_full_unstemmed Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
title_short Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
title_sort wide local excision for merkel cell carcinoma of the lower extremity: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535395/
https://www.ncbi.nlm.nih.gov/pubmed/36277148
http://dx.doi.org/10.3892/etm.2022.11636
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