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Wide local excision for Merkel cell carcinoma of the lower extremity: A case report
Primary Merkel cell carcinoma (MCC) is rare and wide local excision is the primary method of treatment. However, no consensus has been reached on the best surgical approach and research is currently limited. The choice of surgical method depends on the experience of the surgeon and the situation of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535395/ https://www.ncbi.nlm.nih.gov/pubmed/36277148 http://dx.doi.org/10.3892/etm.2022.11636 |
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author | Zhang, Yong Sun, Yan Mo, Juefei |
author_facet | Zhang, Yong Sun, Yan Mo, Juefei |
author_sort | Zhang, Yong |
collection | PubMed |
description | Primary Merkel cell carcinoma (MCC) is rare and wide local excision is the primary method of treatment. However, no consensus has been reached on the best surgical approach and research is currently limited. The choice of surgical method depends on the experience of the surgeon and the situation of the patient. In the present study, the clinical data of a single case of primary MCC that was treated with wide local excision in June 2019 were retrospectively analyzed and the associated literature was reviewed. The patient underwent complete resection of the tumor, which extended 2 cm from the outer edge of the nodule and reached the subcutaneous fat layer. The wound was closed with a tension-relieving suture. The stitches were removed 15 days following surgery and the wound had healed adequately. No recurrence occurred during 30 months of follow-up. However, further multi-center prospective randomized clinical trials are required for further investigation. |
format | Online Article Text |
id | pubmed-9535395 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-95353952022-10-21 Wide local excision for Merkel cell carcinoma of the lower extremity: A case report Zhang, Yong Sun, Yan Mo, Juefei Exp Ther Med Case Report Primary Merkel cell carcinoma (MCC) is rare and wide local excision is the primary method of treatment. However, no consensus has been reached on the best surgical approach and research is currently limited. The choice of surgical method depends on the experience of the surgeon and the situation of the patient. In the present study, the clinical data of a single case of primary MCC that was treated with wide local excision in June 2019 were retrospectively analyzed and the associated literature was reviewed. The patient underwent complete resection of the tumor, which extended 2 cm from the outer edge of the nodule and reached the subcutaneous fat layer. The wound was closed with a tension-relieving suture. The stitches were removed 15 days following surgery and the wound had healed adequately. No recurrence occurred during 30 months of follow-up. However, further multi-center prospective randomized clinical trials are required for further investigation. D.A. Spandidos 2022-09-29 /pmc/articles/PMC9535395/ /pubmed/36277148 http://dx.doi.org/10.3892/etm.2022.11636 Text en Copyright: © Zhang et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Zhang, Yong Sun, Yan Mo, Juefei Wide local excision for Merkel cell carcinoma of the lower extremity: A case report |
title | Wide local excision for Merkel cell carcinoma of the lower extremity: A case report |
title_full | Wide local excision for Merkel cell carcinoma of the lower extremity: A case report |
title_fullStr | Wide local excision for Merkel cell carcinoma of the lower extremity: A case report |
title_full_unstemmed | Wide local excision for Merkel cell carcinoma of the lower extremity: A case report |
title_short | Wide local excision for Merkel cell carcinoma of the lower extremity: A case report |
title_sort | wide local excision for merkel cell carcinoma of the lower extremity: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535395/ https://www.ncbi.nlm.nih.gov/pubmed/36277148 http://dx.doi.org/10.3892/etm.2022.11636 |
work_keys_str_mv | AT zhangyong widelocalexcisionformerkelcellcarcinomaofthelowerextremityacasereport AT sunyan widelocalexcisionformerkelcellcarcinomaofthelowerextremityacasereport AT mojuefei widelocalexcisionformerkelcellcarcinomaofthelowerextremityacasereport |