Cargando…

Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature

Mucoepidermoid carcinoma (MEC) is the most common malignancy of minor salivary glands in adults. Pulmonary MEC is extremely uncommon, comprising only 0.1–0.2% of the primary lung malignancies and <1% of primary bronchial tumors. It is even rarer in children, and literature is limited to a few cas...

Descripción completa

Detalles Bibliográficos
Autores principales: Uppal, Deepak Kumar, Madan, Renu, Peters, Nitin J., Bal, Amanjit, Ballari, Nagarjun, Goyal, Shikha, Khosla, Divya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Radiation Oncology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535415/
https://www.ncbi.nlm.nih.gov/pubmed/36200310
http://dx.doi.org/10.3857/roj.2021.00500
_version_ 1784802768791273472
author Uppal, Deepak Kumar
Madan, Renu
Peters, Nitin J.
Bal, Amanjit
Ballari, Nagarjun
Goyal, Shikha
Khosla, Divya
author_facet Uppal, Deepak Kumar
Madan, Renu
Peters, Nitin J.
Bal, Amanjit
Ballari, Nagarjun
Goyal, Shikha
Khosla, Divya
author_sort Uppal, Deepak Kumar
collection PubMed
description Mucoepidermoid carcinoma (MEC) is the most common malignancy of minor salivary glands in adults. Pulmonary MEC is extremely uncommon, comprising only 0.1–0.2% of the primary lung malignancies and <1% of primary bronchial tumors. It is even rarer in children, and literature is limited to a few case reports only. Here we present a case report of a 9-year-old boy diagnosed with primary MEC of the trachea along with a review of the literature. A 9-year-old male child presented with complaint of dry cough for two years which was later associated with shortness of breath after one year. Bronchoscopic examination revealed a growth arising from right lateral wall of carina occluding 50% of the lumen and detailed histopathological examination revealed it to be a MEC of the trachea. The patient underwent local excision of the tumor with primary anastomosis. Because of positive margin, adjuvant radiotherapy of 60 Gy in 30 fractions was given to the tumor bed. The patient tolerated the treatment well and is disease free at 6 months follow-up. Experience with MEC of the trachea in children is limited, and optimal treatment protocols have not been defined, with current treatment mainly extrapolated from MEC of the salivary glands.
format Online
Article
Text
id pubmed-9535415
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Korean Society for Radiation Oncology
record_format MEDLINE/PubMed
spelling pubmed-95354152022-10-12 Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature Uppal, Deepak Kumar Madan, Renu Peters, Nitin J. Bal, Amanjit Ballari, Nagarjun Goyal, Shikha Khosla, Divya Radiat Oncol J Case Report Mucoepidermoid carcinoma (MEC) is the most common malignancy of minor salivary glands in adults. Pulmonary MEC is extremely uncommon, comprising only 0.1–0.2% of the primary lung malignancies and <1% of primary bronchial tumors. It is even rarer in children, and literature is limited to a few case reports only. Here we present a case report of a 9-year-old boy diagnosed with primary MEC of the trachea along with a review of the literature. A 9-year-old male child presented with complaint of dry cough for two years which was later associated with shortness of breath after one year. Bronchoscopic examination revealed a growth arising from right lateral wall of carina occluding 50% of the lumen and detailed histopathological examination revealed it to be a MEC of the trachea. The patient underwent local excision of the tumor with primary anastomosis. Because of positive margin, adjuvant radiotherapy of 60 Gy in 30 fractions was given to the tumor bed. The patient tolerated the treatment well and is disease free at 6 months follow-up. Experience with MEC of the trachea in children is limited, and optimal treatment protocols have not been defined, with current treatment mainly extrapolated from MEC of the salivary glands. The Korean Society for Radiation Oncology 2022-09 2022-09-29 /pmc/articles/PMC9535415/ /pubmed/36200310 http://dx.doi.org/10.3857/roj.2021.00500 Text en Copyright © 2022 The Korean Society for Radiation Oncology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Uppal, Deepak Kumar
Madan, Renu
Peters, Nitin J.
Bal, Amanjit
Ballari, Nagarjun
Goyal, Shikha
Khosla, Divya
Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
title Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
title_full Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
title_fullStr Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
title_full_unstemmed Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
title_short Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
title_sort mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535415/
https://www.ncbi.nlm.nih.gov/pubmed/36200310
http://dx.doi.org/10.3857/roj.2021.00500
work_keys_str_mv AT uppaldeepakkumar mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature
AT madanrenu mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature
AT petersnitinj mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature
AT balamanjit mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature
AT ballarinagarjun mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature
AT goyalshikha mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature
AT khosladivya mucoepidermoidcarcinomaofthetracheaina9yearoldmalechildcasereportandreviewofliterature