Induced resistance to ifosfamide in osteosarcoma cells suggests a more aggressive tumor profile

AIMS: Osteosarcoma (OS) is the most common primary malignant bone sarcoma among children and adolescents. Treatment is based on neo-adjuvant and adjuvant chemotherapy, using the standard drugs cisplatin, methotrexate, doxorubicin, and ifosfamide (IFO). Due to the high capacity of tumor resistance, t...

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Detalles Bibliográficos
Autores principales: de Oliveira Rodrigues, Maria Tereza, Pereira da Silva, Lucas, Pogue, Robert Edward, de Carvalho, Juliana Lott, Motoyama, Andrea Barretto, de Alencar e Silva, Thuany, Brunel, Hilana dos Santos Sena, de Sá, Maria Fátima Grossi, Vieira de Andrade, Rosângela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535421/
https://www.ncbi.nlm.nih.gov/pubmed/36213144
http://dx.doi.org/10.1016/j.bbrep.2022.101357

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