SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis

BACKGROUND: To determine whether SIRPα can be a diagnostic marker of pulmonary tuberculosis (PTB) and the molecular mechanism of SIRPα regulating macrophages to kill Mycobacterium tuberculosis (MTB). METHODS: Meta-analysis combined with subsequent qRT-PCR, western-blotting and flow cytometry assay w...

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Detalles Bibliográficos
Autores principales: Wang, Di, Lin, Yunkai, Xu, Feihong, Zhang, Hui, Zhu, Xiaoyan, Liu, Zhen, Hu, Yuan, Dong, Guanjun, Sun, Bingqi, Yu, Yanhong, Ma, Guoren, Tang, Zhigang, Legarda, Diana, Ting, Adrian, Liu, Yuan, Hou, Jia, Dong, Liwei, Xiong, Huabao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535427/
https://www.ncbi.nlm.nih.gov/pubmed/36202053
http://dx.doi.org/10.1016/j.ebiom.2022.104278

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