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Pharmaceutical Potential of Casein-Derived Tripeptide Met-Lys-Pro: Improvement in Cognitive Impairments and Suppression of Inflammation in APP/PS1 Mice

BACKGROUND: Tripeptide Met-Lys-Pro (MKP), a component of casein hydrolysates, has effective angiotensin-converting enzyme (ACE) inhibitory activity. Brain angiotensin II enzyme activates the NADPH oxidase complex via angiotensin II receptor type 1 (AT1) and enhances oxidative stress injury. ACE inhi...

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Detalles Bibliográficos
Autores principales: Matsuzaki Tada, Asuka, Hamezah, Hamizah Shahirah, Pahrudin Arrozi, Aslina, Abu Bakar, Zulzikry Hafiz, Yanagisawa, Daijiro, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535549/
https://www.ncbi.nlm.nih.gov/pubmed/35964178
http://dx.doi.org/10.3233/JAD-220192