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Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery

There is evidence that men are more likely to undergo deep brain stimulation (DBS) for Parkinson’s disease (PD), suggesting that women are relatively undertreated. 121 consecutive PD patients undergoing awake DBS with microelectrode recording and intraoperative clinical testing (30 patients, 5 women...

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Detalles Bibliográficos
Autores principales: Vinke, R. Saman, Georgiev, Dejan, Selvaraj, Ashok K., Rahimi, Tahmina, Bloem, Bastiaan R., Bartels, Ronald H.M.A., Esselink, Rianne A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535557/
https://www.ncbi.nlm.nih.gov/pubmed/35754293
http://dx.doi.org/10.3233/JPD-223315
Descripción
Sumario:There is evidence that men are more likely to undergo deep brain stimulation (DBS) for Parkinson’s disease (PD), suggesting that women are relatively undertreated. 121 consecutive PD patients undergoing awake DBS with microelectrode recording and intraoperative clinical testing (30 patients, 5 women) or asleep MRI-guided and CT-verified (91 patients, 38 women) bilateral subthalamic nucleus DBS were included in this study. The results showed an increase in the proportion of female patients from 16.7% to 41.8% after changing our operative technique (OR = 5.61; 95% CI: 1.52–20.78; p = 0.010) from awake to asleep, suggesting that women are more likely to undergo DBS when operated asleep.