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Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery

There is evidence that men are more likely to undergo deep brain stimulation (DBS) for Parkinson’s disease (PD), suggesting that women are relatively undertreated. 121 consecutive PD patients undergoing awake DBS with microelectrode recording and intraoperative clinical testing (30 patients, 5 women...

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Autores principales: Vinke, R. Saman, Georgiev, Dejan, Selvaraj, Ashok K., Rahimi, Tahmina, Bloem, Bastiaan R., Bartels, Ronald H.M.A., Esselink, Rianne A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535557/
https://www.ncbi.nlm.nih.gov/pubmed/35754293
http://dx.doi.org/10.3233/JPD-223315
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author Vinke, R. Saman
Georgiev, Dejan
Selvaraj, Ashok K.
Rahimi, Tahmina
Bloem, Bastiaan R.
Bartels, Ronald H.M.A.
Esselink, Rianne A.J.
author_facet Vinke, R. Saman
Georgiev, Dejan
Selvaraj, Ashok K.
Rahimi, Tahmina
Bloem, Bastiaan R.
Bartels, Ronald H.M.A.
Esselink, Rianne A.J.
author_sort Vinke, R. Saman
collection PubMed
description There is evidence that men are more likely to undergo deep brain stimulation (DBS) for Parkinson’s disease (PD), suggesting that women are relatively undertreated. 121 consecutive PD patients undergoing awake DBS with microelectrode recording and intraoperative clinical testing (30 patients, 5 women) or asleep MRI-guided and CT-verified (91 patients, 38 women) bilateral subthalamic nucleus DBS were included in this study. The results showed an increase in the proportion of female patients from 16.7% to 41.8% after changing our operative technique (OR = 5.61; 95% CI: 1.52–20.78; p = 0.010) from awake to asleep, suggesting that women are more likely to undergo DBS when operated asleep.
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spelling pubmed-95355572022-10-20 Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery Vinke, R. Saman Georgiev, Dejan Selvaraj, Ashok K. Rahimi, Tahmina Bloem, Bastiaan R. Bartels, Ronald H.M.A. Esselink, Rianne A.J. J Parkinsons Dis Short Communication There is evidence that men are more likely to undergo deep brain stimulation (DBS) for Parkinson’s disease (PD), suggesting that women are relatively undertreated. 121 consecutive PD patients undergoing awake DBS with microelectrode recording and intraoperative clinical testing (30 patients, 5 women) or asleep MRI-guided and CT-verified (91 patients, 38 women) bilateral subthalamic nucleus DBS were included in this study. The results showed an increase in the proportion of female patients from 16.7% to 41.8% after changing our operative technique (OR = 5.61; 95% CI: 1.52–20.78; p = 0.010) from awake to asleep, suggesting that women are more likely to undergo DBS when operated asleep. IOS Press 2022-09-02 /pmc/articles/PMC9535557/ /pubmed/35754293 http://dx.doi.org/10.3233/JPD-223315 Text en © 2022 – The authors. Published by IOS Press https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Vinke, R. Saman
Georgiev, Dejan
Selvaraj, Ashok K.
Rahimi, Tahmina
Bloem, Bastiaan R.
Bartels, Ronald H.M.A.
Esselink, Rianne A.J.
Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery
title Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery
title_full Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery
title_fullStr Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery
title_full_unstemmed Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery
title_short Gender Distribution in Deep Brain Stimulation for Parkinson’s Disease: The Effect of Awake versus Asleep Surgery
title_sort gender distribution in deep brain stimulation for parkinson’s disease: the effect of awake versus asleep surgery
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535557/
https://www.ncbi.nlm.nih.gov/pubmed/35754293
http://dx.doi.org/10.3233/JPD-223315
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