Cargando…

Central and Peripheral Inflammation: Connecting the Immune Responses of Parkinson’s Disease

Inflammation has increasingly become a focus of study in regards to Parkinson’s disease (PD). Moreover, both central and peripheral sources of inflammation have been implicated in the pathogenesis of PD. Central inflammation consisting of activated microglia, astroglia, and T cell responses within t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Williams, Gregory P., Schonhoff, Aubrey M., Sette, Alessandro, Lindestam Arlehamn, Cecilia S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535591/ https://www.ncbi.nlm.nih.gov/pubmed/35754290 http://dx.doi.org/10.3233/JPD-223241

Ejemplares similares

Autoimmunity in Parkinson's Disease: The Role of α-Synuclein-Specific T Cells
por: Garretti, Francesca, et al.
Publicado: (2019)

Definition of CD4 Immunosignatures Associated with MTB
por: Lindestam Arlehamn, Cecilia S., et al.
Publicado: (2014)

Lack of evidence for BCG vaccine protection from severe COVID-19
por: Lindestam Arlehamn, Cecilia S., et al.
Publicado: (2020)

Classical CD4 T cells as the cornerstone of antimycobacterial immunity
por: Morgan, Jeffrey, et al.
Publicado: (2021)

Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
por: Dhanwani, Rekha, et al.
Publicado: (2022)

Unaltered T cell responses to common antigens in individuals with Parkinson’s disease
por: Williams, Gregory P., et al.
Publicado: (2023)

Host Transcriptomics as a Tool to Identify Diagnostic and Mechanistic Immune Signatures of Tuberculosis
por: Burel, Julie G., et al.
Publicado: (2019)

Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease
por: Williams, Gregory P., et al.
Publicado: (2018)

CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease
por: Williams, Gregory P, et al.
Publicado: (2021)

The Challenge of Distinguishing Cell–Cell Complexes from Singlet Cells in Non‐Imaging Flow Cytometry and Single‐Cell Sorting
por: Burel, Julie G., et al.
Publicado: (2020)

Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes
por: Paul, Sinu, et al.
Publicado: (2017)

Anti-HIV potency of T-cell responses elicited by dendritic cell therapeutic vaccination
por: Surenaud, Mathieu, et al.
Publicado: (2019)

The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse
por: Singhania, Akul, et al.
Publicado: (2021)

Automatic Generation of Validated Specific Epitope Sets
por: Carrasco Pro, Sebastian, et al.
Publicado: (2015)

Disease extent and anti‐tubercular treatment response correlates with Mycobacterium tuberculosis‐specific CD4 T‐cell phenotype regardless of HIV‐1 status
por: Riou, Catherine, et al.
Publicado: (2020)

Editorial: Exploring Immune Variability in Susceptibility to Tuberculosis Infection in Humans
por: Seshadri, Chetan, et al.
Publicado: (2022)

Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice
por: Patankar, Yash R., et al.
Publicado: (2019)

Pseudomonas aeruginosa pilin activates the inflammasome
por: Lindestam Arlehamn, Cecilia S, et al.
Publicado: (2011)

Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis
por: Du Bruyn, Elsa, et al.
Publicado: (2020)

A Review on T Cell Epitopes Identified Using Prediction and Cell-Mediated Immune Models for Mycobacterium tuberculosis and Bordetella pertussis
por: Tian, Yuan, et al.
Publicado: (2018)

Immune Responses in Parkinson's Disease: Interplay between Central and Peripheral Immune Systems
por: Su, Xiaomin, et al.
Publicado: (2014)

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
por: Lindestam Arlehamn, Cecilia S., et al.
Publicado: (2020)

Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4(+) T Cell Responses
por: da Silva Antunes, Ricardo, et al.
Publicado: (2017)

Correction: Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4(+) T Cell Responses
por: da Silva Antunes, Ricardo, et al.
Publicado: (2018)

Imprinting of Gut-Homing Receptors on Mtb-Specific Th1* Cells Is Associated with Reduced Lung Homing after Gavage BCG Vaccination of Rhesus Macaques
por: Hoft, Stella G., et al.
Publicado: (2023)

T Cell Responses to Neural Autoantigens Are Similar in Alzheimer’s Disease Patients and Age-Matched Healthy Controls
por: Dhanwani, Rekha, et al.
Publicado: (2020)

Corrigendum: T Cell Responses to Neural Autoantigens Are Similar in Alzheimer's Disease Patients and Age-Matched Healthy Controls
por: Dhanwani, Rekha, et al.
Publicado: (2021)

Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes
por: Carrasco Pro, Sebastian, et al.
Publicado: (2018)

T cells of Parkinson’s disease patients recognize α–synuclein peptides
por: Sulzer, David, et al.
Publicado: (2017)

The Role of Potassium in Inflammasome Activation by Bacteria
por: Arlehamn, Cecilia S. Lindestam, et al.
Publicado: (2010)

Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile
por: Chihab, Leila Y., et al.
Publicado: (2022)

T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer’s disease
por: Grayson, Jason M., et al.
Publicado: (2023)

Quantitative and Qualitative Perturbations of CD8(+) MAITs in Healthy Mycobacterium tuberculosis–Infected Individuals
por: Pomaznoy, Mikhail, et al.
Publicado: (2020)

Antigen-specificity measurements are the key to understanding T cell responses
por: Tippalagama, Rashmi, et al.
Publicado: (2023)

CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature
por: Singhania, Akul, et al.
Publicado: (2021)

The biomarkers of immune dysregulation and inflammation response in Parkinson disease
por: Chen, Li, et al.
Publicado: (2016)

A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans
por: Lindestam Arlehamn, Cecilia S., et al.
Publicado: (2016)

Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection
por: Riou, Catherine, et al.
Publicado: (2021)

MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies
por: White, Andrew D., et al.
Publicado: (2021)

LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson’s
por: Wallings, Rebecca L., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b8a7n2bvau7c900kcheso4bcsr