Cargando…
Porphyromonas gingivalis Conditioned Medium Induces Amyloidogenic Processing of the Amyloid-β Protein Precursor upon in vitro Infection of SH-SY5Y Cells
BACKGROUND: Cleavage of the amyloid-β protein precursor (AβPP) mediated by host secretase enzymes, releases several fragments including amyloid-β (Aβ(40) and Aβ(42)). OBJECTIVE: To determine if Porphyromonas gingivalis conditioned medium cleaved AβPP to release Aβ(40) and Aβ(42). METHODS: The SH-SY5...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
IOS Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535609/ https://www.ncbi.nlm.nih.gov/pubmed/36275415 http://dx.doi.org/10.3233/ADR-220029 |