Synthesis of 7-Aminocoumarins from 7-Hydroxycoumarins via Amide Smiles Rearrangement

[Image: see text] N-Substituted 7-aminocoumarins can be synthesized from readily available 7-hydroxycoumarins via alkylation with α-bromoacetamides and subsequent tandem O → N Smiles rearrangement–amide hydrolysis. The key rearrangement sequence proceeds under mild conditions to provide convenient a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lippe, Daniel S., Elghawy, Omar, Zucker, Adam M., Yanagawa, Evan S. K., Mathews, Erin, Ahmed, Yusef G., D’Elia, Paige N., Bimson, Sabrina, Walvoord, Ryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535735/
https://www.ncbi.nlm.nih.gov/pubmed/36211046
http://dx.doi.org/10.1021/acsomega.2c04653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535735/
https://www.ncbi.nlm.nih.gov/pubmed/36211046
http://dx.doi.org/10.1021/acsomega.2c04653

Ejemplares similares