CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation

CDK9 is a kinase critical for the productive transcription of protein‐coding genes by RNA polymerase II (pol II). As part of P‐TEFb, CDK9 phosphorylates the carboxyl‐terminal domain (CTD) of pol II and elongation factors, which allows pol II to elongate past the early elongation checkpoint (EEC) enc...

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Autores principales: Tellier, Michael, Zaborowska, Justyna, Neve, Jonathan, Nojima, Takayuki, Hester, Svenja, Fournier, Marjorie, Furger, Andre, Murphy, Shona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535751/
https://www.ncbi.nlm.nih.gov/pubmed/35980303
http://dx.doi.org/10.15252/embr.202154520

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