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Identification and characterization of in vitro expanded hematopoietic stem cells

Hematopoietic stem cells (HSCs) cultured outside the body are the fundamental component of a wide range of cellular and gene therapies. Recent efforts have achieved > 200‐fold expansion of functional HSCs, but their molecular characterization has not been possible since the majority of cells are...

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Detalles Bibliográficos
Autores principales: Che, James L C, Bode, Daniel, Kucinski, Iwo, Cull, Alyssa H, Bain, Fiona, Becker, Hans J, Jassinskaja, Maria, Barile, Melania, Boyd, Grace, Belmonte, Miriam, Zeng, Andy G X, Igarashi, Kyomi J, Rubio‐Lara, Juan, Shepherd, Mairi S, Clay, Anna, Dick, John E, Wilkinson, Adam C, Nakauchi, Hiromitsu, Yamazaki, Satoshi, Göttgens, Berthold, Kent, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535767/
https://www.ncbi.nlm.nih.gov/pubmed/35971894
http://dx.doi.org/10.15252/embr.202255502