Lint‐O cooperates with L(3)mbt in target gene suppression to maintain homeostasis in fly ovary and brain

Loss‐of‐function mutations in Drosophila lethal(3)malignant brain tumor [l(3)mbt] cause ectopic expression of germline genes and brain tumors. Loss of L(3)mbt function in ovarian somatic cells (OSCs) aberrantly activates germ‐specific piRNA amplification and leads to infertility. However, the underl...

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Autores principales: Yamamoto‐Matsuda, Hitomi, Miyoshi, Keita, Moritoh, Mai, Yoshitane, Hikari, Fukada, Yoshitaka, Saito, Kuniaki, Yamanaka, Soichiro, Siomi, Mikiko C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535798/
https://www.ncbi.nlm.nih.gov/pubmed/35993198
http://dx.doi.org/10.15252/embr.202153813

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