Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K

The low (90 K) and room (298 K) temperature crystal structures of topiramate azido­sulfate [systematic name 2,3:4,5-bis-O-(1-methyl­ethyl­idene)-β-d-fructo­pyran­ose azido­sulfate], C(12)H(19)N(3)O(8)S, an inter­mediate in the synthesis of the anti-convulsant drug topiramate, are described. Topirama...

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Autores principales: Priyanka, Prabhakar, Jayanna, Bidarur K., Kiran Kumar, Haruvegowda, Vinaya, Divakara, Thayamma R., Yathirajan, Hemmige S., Glidewell, Christopher, Parkin, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535817/
https://www.ncbi.nlm.nih.gov/pubmed/36250107
http://dx.doi.org/10.1107/S2056989022008799
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author Priyanka, Prabhakar
Jayanna, Bidarur K.
Kiran Kumar, Haruvegowda
Vinaya,
Divakara, Thayamma R.
Yathirajan, Hemmige S.
Glidewell, Christopher
Parkin, Sean
author_facet Priyanka, Prabhakar
Jayanna, Bidarur K.
Kiran Kumar, Haruvegowda
Vinaya,
Divakara, Thayamma R.
Yathirajan, Hemmige S.
Glidewell, Christopher
Parkin, Sean
author_sort Priyanka, Prabhakar
collection PubMed
description The low (90 K) and room (298 K) temperature crystal structures of topiramate azido­sulfate [systematic name 2,3:4,5-bis-O-(1-methyl­ethyl­idene)-β-d-fructo­pyran­ose azido­sulfate], C(12)H(19)N(3)O(8)S, an inter­mediate in the synthesis of the anti-convulsant drug topiramate, are described. Topiramate azido­sulfate (I) finds use as a reference impurity standard for topiramate. A modified synthesis and some spectroscopic details are also presented.
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spelling pubmed-95358172022-10-13 Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K Priyanka, Prabhakar Jayanna, Bidarur K. Kiran Kumar, Haruvegowda Vinaya, Divakara, Thayamma R. Yathirajan, Hemmige S. Glidewell, Christopher Parkin, Sean Acta Crystallogr E Crystallogr Commun Research Communications The low (90 K) and room (298 K) temperature crystal structures of topiramate azido­sulfate [systematic name 2,3:4,5-bis-O-(1-methyl­ethyl­idene)-β-d-fructo­pyran­ose azido­sulfate], C(12)H(19)N(3)O(8)S, an inter­mediate in the synthesis of the anti-convulsant drug topiramate, are described. Topiramate azido­sulfate (I) finds use as a reference impurity standard for topiramate. A modified synthesis and some spectroscopic details are also presented. International Union of Crystallography 2022-09-08 /pmc/articles/PMC9535817/ /pubmed/36250107 http://dx.doi.org/10.1107/S2056989022008799 Text en © Priyanka et al. 2022 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Priyanka, Prabhakar
Jayanna, Bidarur K.
Kiran Kumar, Haruvegowda
Vinaya,
Divakara, Thayamma R.
Yathirajan, Hemmige S.
Glidewell, Christopher
Parkin, Sean
Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K
title Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K
title_full Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K
title_fullStr Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K
title_full_unstemmed Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K
title_short Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K
title_sort synthesis and crystal structure of topiramate azido­sulfate at 90 k and 298 k
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535817/
https://www.ncbi.nlm.nih.gov/pubmed/36250107
http://dx.doi.org/10.1107/S2056989022008799
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