Examining evidence of time-dependent treatment effects: an illustration using regression methods

BACKGROUND: For the design and analysis of clinical trials with time-to-event outcomes, the Cox proportional hazards model and the logrank test have been the cornerstone methods for many decades. Increasingly, the key assumption of proportionality—or time-fixed effects—that underpins these methods h...

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Detalles Bibliográficos
Autores principales: Jachno, Kim M., Heritier, Stephane, Woods, Robyn L., Mahady, Suzanne, Chan, Andrew, Tonkin, Andrew, Murray, Anne, McNeil, John J., Wolfe, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535854/
https://www.ncbi.nlm.nih.gov/pubmed/36203169
http://dx.doi.org/10.1186/s13063-022-06803-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535854/
https://www.ncbi.nlm.nih.gov/pubmed/36203169
http://dx.doi.org/10.1186/s13063-022-06803-x

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