Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ’s Oligomers Cytotoxicity In Vitro

[Image: see text] Alzheimer’s disease (AD) is a progressive neurodegenerative condition affecting people in the elderly. Targeting aggregation of β-amyloid peptides (Aβ) is considered a promising approach for the therapeutic treatment of the disease. Peptide based inhibitors of β-amyloid fibrillatio...

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Detalles Bibliográficos
Autores principales: Consoli, Grazia Maria Letizia, Tosto, Rita, Baglieri, Ausilia, Petralia, Salvatore, Campagna, Tiziana, Di Natale, Giuseppe, Zimbone, Stefania, Giuffrida, Maria Laura, Pappalardo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535895/
https://www.ncbi.nlm.nih.gov/pubmed/33844495
http://dx.doi.org/10.1021/acschemneuro.1c00117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535895/
https://www.ncbi.nlm.nih.gov/pubmed/33844495
http://dx.doi.org/10.1021/acschemneuro.1c00117

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