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Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ’s Oligomers Cytotoxicity In Vitro

[Image: see text] Alzheimer’s disease (AD) is a progressive neurodegenerative condition affecting people in the elderly. Targeting aggregation of β-amyloid peptides (Aβ) is considered a promising approach for the therapeutic treatment of the disease. Peptide based inhibitors of β-amyloid fibrillatio...

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Detalles Bibliográficos
Autores principales:	Consoli, Grazia Maria Letizia, Tosto, Rita, Baglieri, Ausilia, Petralia, Salvatore, Campagna, Tiziana, Di Natale, Giuseppe, Zimbone, Stefania, Giuffrida, Maria Laura, Pappalardo, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535895/ https://www.ncbi.nlm.nih.gov/pubmed/33844495 http://dx.doi.org/10.1021/acschemneuro.1c00117

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