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Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications

A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 (COVID-19). The interaction between SARS-CoV-2 and angiotensin-converting enzyme 2 (ACE2) triggers the activation of the NACHT,...

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Detalles Bibliográficos
Autores principales: Potere, Nicola, Del Buono, Marco Giuseppe, Caricchio, Roberto, Cremer, Paul C., Vecchié, Alessandra, Porreca, Ettore, Dalla Gasperina, Daniela, Dentali, Francesco, Abbate, Antonio, Bonaventura, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536001/
https://www.ncbi.nlm.nih.gov/pubmed/36209522
http://dx.doi.org/10.1016/j.ebiom.2022.104299

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