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Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis

Merkel Cell Carcinoma (MCC) is a rare dermatologic malignancy with significant morbidity and mortality associated with metastatic disease. In this case, we discuss and extremely rare presentation of MCC with metastasis to the stomach in a patient that presented with profound anemia. Unfortunately, m...

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Autores principales: Eagle, Zachary, Essien, Francis, Shahin, George, Jones, Amia, McKee, John, Elkins, Camille, Juakiem, Wassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536094/
https://www.ncbi.nlm.nih.gov/pubmed/36211630
http://dx.doi.org/10.1177/11795476221112382
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author Eagle, Zachary
Essien, Francis
Shahin, George
Jones, Amia
McKee, John
Elkins, Camille
Juakiem, Wassem
author_facet Eagle, Zachary
Essien, Francis
Shahin, George
Jones, Amia
McKee, John
Elkins, Camille
Juakiem, Wassem
author_sort Eagle, Zachary
collection PubMed
description Merkel Cell Carcinoma (MCC) is a rare dermatologic malignancy with significant morbidity and mortality associated with metastatic disease. In this case, we discuss and extremely rare presentation of MCC with metastasis to the stomach in a patient that presented with profound anemia. Unfortunately, mortality following diagnosis of MCC with gastric metastasis approaches 67% at 4 months based on available published reports. Due to its rarity and high rate of mortality, there is a lack of available research and literature to help guide treatment of this rare presentation of MCC. This case report presents a positive outcome associated with a partial gastrectomy for the treatment of symptomatic MCC with gastric metastasis and continued survival with persistently stable hemoglobin at 12 months. KEY CLINICAL MESSAGE: Anemia may be a significant cause of the morbidity and mortality associated with MCC with gastric metastasis. Our case demonstrates a positive outcome associated with partial gastric resection and presents a possible treatment option for this rare disease process.
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spelling pubmed-95360942022-10-07 Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis Eagle, Zachary Essien, Francis Shahin, George Jones, Amia McKee, John Elkins, Camille Juakiem, Wassem Clin Med Insights Case Rep Case Report Merkel Cell Carcinoma (MCC) is a rare dermatologic malignancy with significant morbidity and mortality associated with metastatic disease. In this case, we discuss and extremely rare presentation of MCC with metastasis to the stomach in a patient that presented with profound anemia. Unfortunately, mortality following diagnosis of MCC with gastric metastasis approaches 67% at 4 months based on available published reports. Due to its rarity and high rate of mortality, there is a lack of available research and literature to help guide treatment of this rare presentation of MCC. This case report presents a positive outcome associated with a partial gastrectomy for the treatment of symptomatic MCC with gastric metastasis and continued survival with persistently stable hemoglobin at 12 months. KEY CLINICAL MESSAGE: Anemia may be a significant cause of the morbidity and mortality associated with MCC with gastric metastasis. Our case demonstrates a positive outcome associated with partial gastric resection and presents a possible treatment option for this rare disease process. SAGE Publications 2022-10-03 /pmc/articles/PMC9536094/ /pubmed/36211630 http://dx.doi.org/10.1177/11795476221112382 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Eagle, Zachary
Essien, Francis
Shahin, George
Jones, Amia
McKee, John
Elkins, Camille
Juakiem, Wassem
Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis
title Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis
title_full Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis
title_fullStr Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis
title_full_unstemmed Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis
title_short Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis
title_sort partial gastric resection for symptomatic anemia following diagnosis of merkel cell carcinoma (mcc) of the skin with gastric metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536094/
https://www.ncbi.nlm.nih.gov/pubmed/36211630
http://dx.doi.org/10.1177/11795476221112382
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